Our team of experts possesses extensive experience in understanding the pathogenesis, progression, and potential therapeutic targets of a wide range of cancers. We are proficient in a variety of in vitro and in vivo cancer treatment assays, capable of evaluating the efficacy, safety, and pharmacokinetic properties of potential anti-cancer compounds, cellular therapies, and gene-editing technologies.
Our experts have significant experience in radiation biology and DNA damade response mechanisms. Additionally, Southern Research has strong immunology expertise to complement our cancer research services.
Comprehensive Services Spanning the Cancer Treatment Spectrum
We offer a comprehensive suite of preclinical cancer treatment services tailored to address the diverse challenges posed by this disease, encompassing every stage of the research process:
Cancer Cell Line Characterization and Development: We help you establish and characterize relevant cancer cell lines, providing crucial models for investigating cancer biology and evaluating therapeutic interventions.
Target Identification and Validation: We employ advanced molecular and genetic techniques to identify and validate novel therapeutic targets in a wide range of cancers, laying the foundation for effective drug discovery efforts and personalized medicine approaches.
Anti-Cancer Compound, Cellular Therapy, Biologics, and Nucleotide-Based Technology Screening and Optimization: We utilize a range of in vitro and in vivo screening assays to identify promising anti-cancer compounds, cellular therapies, and gene-editing technologies, optimizing their potency, selectivity, and safety profile.
Pharmacokinetic and Pharmacodynamic (PK/PD) & Biodistribution Studies: We determine the absorption, distribution, metabolism, and excretion (ADME) properties of potential anti-cancer compounds, cellular therapies, and gene-editing technologies, providing valuable insights into their pharmacokinetic profiles and pharmacodynamic effects in various cancer models.
Regulatory Support and IND/IDE Preparation: We guide you through the intricate regulatory landscape, ensuring compliance with FDA guidelines and facilitating the preparation of Investigational New Drug (IND) and Investigational Device Exemption (IDE) applications.