In the intricate world of drug development and product safety, understanding the absorption, distribution, metabolism, and excretion (ADME) of a substance is paramount. Our contract research organization (CRO) stands as your trusted partner, providing comprehensive toxicokinetics research services to illuminate the fate of your substance in the body and to safeguard human health.
With a team of experienced toxicologists, we offer a comprehensive suite of toxicokinetics research services, tailored to your specific needs. Our expertise encompasses:
Pharmacokinetic (PK) Studies: Evaluate the absorption, distribution, metabolism, and excretion (ADME) of your substance in various animal models, providing essential data for predicting its behavior in humans.
Toxicokinetic (TK) Studies: Assess the relationship between the concentration of your substance in the body and its potential toxicity, guiding informed dose selection and safety assessment.
Bioanalytical Method Development and Validation: Develop and validate sensitive and reliable methods for quantifying your substance in biological matrices, essential for pharmacokinetic and toxicokinetic studies.
Toxicokinetic Modeling and Simulation: Utilize sophisticated modeling and simulation techniques to predict the ADME of your substance in extrapolating animal exposure data to human and accelerating drug development.
Regulatory Support: Navigate the complexities of global safety testing regulations, ensuring compliance with regulatory requirements for toxicokinetic endpoints in safety studies.
Expert Consulting: Gain insights from our experienced toxicokinetic scientists, who provide expert guidance on all aspects of toxicokinetic study design, data interpretation, and regulatory compliance.
